SCHEMBL4242937

SCHEMBL4242937

O=C(O)C1=C(O)C(CC2CCCCC2)CNC1=O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.36
P4HB P07237 1/20 0.36
GLA P06280 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ATM Q13315 2/20 0.32
MAPT P10636 2/20 0.32
NAAA Q02083 5/20 0.32
MEN1 O00255 1/20 0.31
KDM6B O15054 1/20 0.31
KDM4A O75164 1/20 0.31
KDM4D Q6B0I6 1/20 0.31
KDM3B Q7LBC6 1/20 0.31
HIF1AN Q9NWT6 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31
ASAH1 Q13510 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4243209 0.83 ALDH1A1 (0.34) KMT2AP4HBGLATDP1ATM
SCHEMBL9867761 0.76 NR0B1 (0.35) KMT2AP4HBKDM6BKDM4AKDM4D
SCHEMBL4237870 0.76 NR0B1 (0.35) KMT2AP4HBKDM6BKDM4AKDM4D
SCHEMBL13743332 0.73 RXFP1 (0.44) KMT2AMAPTMEN1
SCHEMBL6684780 0.70 MAPT (0.40) KMT2AP4HBGLATDP1ATM
SCHEMBL28560703 0.63 KDM4E (0.43)
Bicarbonate SCHEMBL3901610 0.62 LMNA (0.43) KMT2A
SCHEMBL6980239 0.60 CTSD (0.43) KMT2AATMMAPTMEN1
SCHEMBL11244055 0.58 ARG1 (0.51) KMT2AMEN1
SCHEMBL1812137 0.58 ARG1 (0.51) KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090203694-A1 INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE HURLEY TIMOTHY BRIAN 2009-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203694-A1 INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE FDPS, UMPS, GGPS1 KMT2A 4780/4885P4HB 514/4885GLA 1984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.