Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008916 | 0.78 | KDM1A (0.46) | KDM1ASLC6A4MTNR1AIDO1SLC6A2 | |
| SCHEMBL6762351 | 0.77 | KDM1A (0.49) | KDM1ASLC6A4MTNR1AIDO1SLC6A2 | |
| SCHEMBL7650798 | 0.77 | KDM1A (0.44) | KDM1ASLC6A4MTNR1AIDO1SLC6A2 | |
| SCHEMBL10420727 | 0.75 | MTNR1A (0.44) | KDM1ASLC6A4MTNR1AIDO1SLC6A2 | |
| SCHEMBL30477104 | 0.74 | SLC6A4 (0.59) | KDM1ASLC6A4MTNR1AIDO1SLC6A2 | |
| SCHEMBL248440 | 0.74 | SLC6A4 (0.59) | KDM1ASLC6A4MTNR1AIDO1SLC6A2 | |
| SCHEMBL15670566 | 0.74 | KDM1A (0.50) | KDM1ASLC6A4MTNR1AIDO1SLC6A2 | |
| SCHEMBL5408925 | 0.74 | KDM1A (0.46) | KDM1ASLC6A4MTNR1AIDO1SLC6A2 | |
| SCHEMBL16398286 | 0.74 | KDM1A (0.46) | KDM1ASLC6A4MTNR1AIDO1SLC6A2 | |
| SCHEMBL3968194 | 0.71 | SLC6A4 (0.56) | KDM1ASLC6A4MTNR1AIDO1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0914333-B1 | PEPTIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-11-24 | — | — | EP | disclosed |
| EP-0932618-B1 | PEPTIDE ANALOGUES CONTAINING A 7-MEMBERED LACTAM RING | ASTRAZENECA AB (SE) | 2003-12-10 | — | — | EP | disclosed |
| CN-1130372-C | Peptide derivatives | ZENECA LTD (GB) | 2003-12-10 | — | — | CN | disclosed |
| US-20030195158-A1 | Peptide derivatives | SYNGENTA LIMITED (GB) | 2003-10-16 | — | — | US | disclosed |
| EP-0946589-B1 | INHIBITORS OF PEPTIDE BINDING TO MHC CLASS II PROTEINS | ASTRAZENECA AB (SE) | 2003-10-01 | — | — | EP | disclosed |
| CN-1116305-C | Peptide derivatives | ZENECA LTD (GB) | 2003-07-30 | — | — | CN | disclosed |
| US-6541453-B2 | Amino acid sequences for use in the treatment of autoimmune or inflammatory diseases | SYNGENTA LIMITED (GB) | 2003-04-01 | — | — | US | disclosed |
| US-20020187934-A1 | Peptide derivatives | SYNGENTA LIMITED (GB) | 2002-12-12 | — | — | US | disclosed |
| US-20020103335-A1 | PEPTIDE DERIVATIVES | ASTRAZENECA UK LIMITED (GB) | 2002-08-01 | — | — | US | disclosed |
| US-6355617-B1 | PEPTIDES, HYDROPHOBIC RESIDUES, AMINO ACIDS AND SEQUENCE | SYNGENTA LIMITED (GB) | 2002-03-12 | — | — | US | disclosed |
| EP-0932618-A1 | PEPTIDE ANALOGUES CONTAINING A 7-MEMBERED LACTAM RING | AstraZeneca AB (SE) | 1999-08-04 | — | — | EP | disclosed |
| CN-1221424-A | Peptide derivatives | ZENECA LTD (GB) | 1999-06-30 | — | — | CN | disclosed |
| EP-0914333-A1 | PEPTIDE DERIVATIVES | ZENECA LIMITED (GB) | 1999-05-12 | — | — | EP | disclosed |
| CN-1213379-A | Peptide derivatives | ZENECA LTD (GB) | 1999-04-07 | — | — | CN | disclosed |
| EP-0882066-A1 | PEPTIDE DERIVATIVES | ZENECA LIMITED (GB) | 1998-12-09 | — | — | EP | disclosed |
| WO-1998025951-A1 | INHIBITORS OF PEPTIDE BINDING TO MHC CLASS II PROTEINS | ZENECA LIMITED (GB) | 1998-06-18 | — | — | WO | disclosed |
| WO-1998023644-A1 | PEPTIDE DERIVATIVES | ZENECA LIMITED (GB) | 1998-06-04 | — | — | WO | disclosed |
| WO-1998017680-A1 | PEPTIDE ANALOGUES CONTAINING A 7-MEMBERED LACTAM RING | ZENECA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |
| WO-1997046578-A1 | PEPTIDE DERIVATIVES | ZENECA LIMITED (GB) | 1997-12-11 | — | — | WO | disclosed |
| WO-1997031023-A1 | PEPTIDE DERIVATIVES | ZENECA LIMITED (GB) | 1997-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195158-A1 | Peptide derivatives | HLA-DRB1, MICA, CD74 | KDM1A 4626/4885SLC6A4 3340/4885MTNR1A 3980/4885 |
| US-20020103335-A1 | PEPTIDE DERIVATIVES | HLA-DRB1, MICA, TAP1 | KDM1A 3567/4885SLC6A4 2540/4885MTNR1A 840/4885 |
| US-20020187934-A1 | Peptide derivatives | HLA-DRB1, MICA, TAP1 | KDM1A 3667/4885SLC6A4 3729/4885MTNR1A 440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.