SCHEMBL6685159

SCHEMBL6685159

COCCC([O])N1CCCC1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
FDPS P14324 2/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 2/20 0.31
SLC6A3 Q01959 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6684791 0.84 MAPT (0.35) ALDH1A1TDP1FDPS
SCHEMBL6692853 0.80 ALDH1A1 (0.33) ALDH1A1TDP1FDPS
SCHEMBL27872501 0.76 SIGMAR1 (0.34) ALDH1A1TDP1
SCHEMBL6686417 0.75 SLC6A3 (0.42) SLC6A2SLC6A4SLC6A3
SCHEMBL17850631 0.74 ALDH1A1 (0.33) ALDH1A1TDP1FDPSSLC6A2SLC6A4
SCHEMBL6539305 0.73 SLC6A3 (0.41) SLC6A2SLC6A4SLC6A3
SCHEMBL5718231 0.71 MAPT (0.40) ALDH1A1TDP1SLC6A2SLC6A4SLC6A3
SCHEMBL5718207 0.71 MAPT (0.40) ALDH1A1TDP1SLC6A2SLC6A4SLC6A3
SCHEMBL27873564 0.71 SLC6A3 (0.36) SLC6A2SLC6A4SLC6A3
SCHEMBL2452380 0.70 HRH3 (0.42) ALDH1A1TDP1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004069145-A2 ANTICANCER COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DR. REDDY'S LABORATORIES LTD. (IN) 2004-08-19 WO disclosed