Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685159 | 0.84 | ALDH1A1 (0.33) | ALDH1A1TDP1FDPS | |
| SCHEMBL6539573 | 0.79 | L3MBTL1 (0.41) | MAPTMAPK1NPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL6692853 | 0.78 | ALDH1A1 (0.33) | MAPTMAPK1NPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL2452380 | 0.76 | HRH3 (0.42) | MAPTMAPK1NPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL6539305 | 0.71 | SLC6A3 (0.41) | — | |
| SCHEMBL4785482 | 0.69 | DPP7 (0.36) | L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL6686417 | 0.69 | SLC6A3 (0.42) | — | |
| SCHEMBL29061476 | 0.67 | FDPS (0.38) | FDPS | |
| SCHEMBL1262872 | 0.66 | FDPS (0.36) | MAPTMAPK1NPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL10103385 | 0.66 | HRH3 (0.61) | L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069145-A2 | ANTICANCER COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-08-19 | — | — | WO | disclosed |