SCHEMBL6685348

SCHEMBL6685348

CC(C)(C)OC(=O)/C(F)=C(\F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.32
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6685352 1.00 DGAT1 (0.32) DGAT1CA14
SCHEMBL10923055 0.78 MAPT (0.42)
SCHEMBL10923053 0.78 MAPT (0.42)
SCHEMBL5147015 0.78 DGAT1 (0.36) DGAT1
SCHEMBL3836211 0.73 DGAT1 (0.36) DGAT1CA14
SCHEMBL5886622 0.73 ALDH1A1 (0.35) DGAT1CA14
SCHEMBL31174520 0.72 DGAT1 (0.39) DGAT1
SCHEMBL10921534 0.71 ALDH1A1 (0.42)
SCHEMBL28499881 0.71 DGAT1 (0.31) DGAT1
SCHEMBL10928381 0.71 ALDH1A1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1476788-A2 FLUORINATED MOLECULES AND METHODS OF MAKING AND USING SAME Honeywell International Inc. (US) 2004-11-17 EP claimed
US-20030232276-A1 Polymers derived from fluoroalkyl norbornenes, fluorinated crotonates, and/or fluorinated allyl alcohols; Diels Alder reaction of a fluorinated crotonate with cyclopentadiene to form said norbornene; photoresists; dielectrics, light guides HONEYWELL INTERNATIONAL INC. 2003-12-18 US claimed
WO-2003073169-A2 FLUORINATED MOLECULES AND METHODS OF MAKING AND USING SAME HONEYWELL INTERNATIONAL INC. (US) 2003-09-04 WO claimed
EP-1476788-A2 FLUORINATED MOLECULES AND METHODS OF MAKING AND USING SAME Honeywell International Inc. (US) 2004-11-17 EP disclosed
US-20030232276-A1 Polymers derived from fluoroalkyl norbornenes, fluorinated crotonates, and/or fluorinated allyl alcohols; Diels Alder reaction of a fluorinated crotonate with cyclopentadiene to form said norbornene; photoresists; dielectrics, light guides HONEYWELL INTERNATIONAL INC. 2003-12-18 US disclosed
WO-2003073169-A2 FLUORINATED MOLECULES AND METHODS OF MAKING AND USING SAME HONEYWELL INTERNATIONAL INC. (US) 2003-09-04 WO disclosed