Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784315 | 0.78 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL78520 | 0.76 | DGAT1 (0.46) | DGAT1CA14 | |
| SCHEMBL14520200 | 0.75 | DGAT1 (0.33) | DGAT1CA14 | |
| SCHEMBL196496 | 0.75 | DGAT1 (0.33) | DGAT1CA14 | |
| SCHEMBL29399642 | 0.74 | — | — | |
| SCHEMBL6685352 | 0.73 | DGAT1 (0.32) | DGAT1CA14 | |
| SCHEMBL6685348 | 0.73 | DGAT1 (0.32) | DGAT1CA14 | |
| SCHEMBL5886622 | 0.73 | ALDH1A1 (0.35) | DGAT1CA14 | |
| SCHEMBL31174520 | 0.72 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL486217 | 0.72 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190716-A1 | FURO- AND THIENO-PYRIDINE CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION | 2017-07-06 | — | — | US | disclosed |
| US-9556197-B2 | Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors | INCYTE CORPORATION (US) | 2017-01-31 | — | — | US | disclosed |
| EP-1581557-B1 | METASTIN DERIVATIVES AND THEIR USE | TAKEDA PHARMACEUTICAL (JP) | 2009-09-23 | — | — | EP | disclosed |
| EP-1581557-A2 | METASTIN DERIVATIVES AND THEIR USE | Takeda Pharmaceutical Company Limited (JP) | 2005-10-05 | — | — | EP | disclosed |
| US-6800611-B2 | ANTICANCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-10-05 | — | — | US | disclosed |
| WO-2004060264-A2 | METASTIN DERIVATIVES AND THEIR USE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (US) | 2004-07-22 | — | — | WO | disclosed |
| US-20040142875-A1 | \"metastin\" is the ligand to a G-protein-coupled orphan receptor known as OT7T175 or AXOR12; prodrug; treating cancer, hydatid mole, invasive mole, miscarriage, fetal hypoplasia, sugar dysbolism, lipid dysbolism or labor induction in a mammal | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-22 | — | — | US | disclosed |
| US-4335043-A | Substituted N-methylene derivatives of thienamycin | MERCK & CO., INC. (US) | 1982-06-15 | — | — | US | disclosed |
| US-4311704-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1982-01-19 | — | — | US | disclosed |
| US-4309438-A | BACTERICIDES | MERCK & CO., INC. (US) | 1982-01-05 | — | — | US | disclosed |
| US-4235920-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-11-25 | — | — | US | disclosed |
| US-4235917-A | N-Alkyl-N-acyl derivatives of thienamycin | MERCK & CO., INC. (US) | 1980-11-25 | — | — | US | disclosed |
| US-4194047-A | Substituted N-methylene derivatives of thienamycin | MERCK & CO., INC. (US) | 1980-03-18 | — | — | US | disclosed |
| US-4172144-A | Schiff's base derivatives of thienamycin | MERCK & CO., INC. (US) | 1979-10-23 | — | — | US | disclosed |
| US-4150145-A | ANTIBIOTIC, BACTERICIDES | MERCK & CO., INC. (US) | 1979-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190716-A1 | FURO- AND THIENO-PYRIDINE CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | PIM1, PIM2, PIM3 | DGAT1 3678/4885CA14 4650/4885 |
| US-20040142875-A1 | \"metastin\" is the ligand to a G-protein-coupled orphan receptor known as OT7T175 or AXOR12; prodrug; treating cancer, hydatid mole, invasive mole, miscarriage, fetal hypoplasia, sugar dysbolism, lipid dysbolism or labor induction in a mammal | GPR27, GPR132, LPAR3 | DGAT1 733/4885CA14 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.