Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.54 |
| ▸ | CTSL | P07711 | 11/20 | 0.54 |
| ▸ | CTSK | P43235 | 10/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686917 | 1.00 | CTSS (0.54) | CTSSCTSLCTSKEPHX2EPHX1 | |
| SCHEMBL5499131 | 0.87 | CTSS (0.57) | CTSSCTSLCTSKALDH1A1 | |
| SCHEMBL6686843 | 0.86 | CTSS (0.45) | CTSSCTSLCTSKEPHX1ALDH1A1 | |
| SCHEMBL5404869 | 0.84 | CTSS (0.48) | CTSSCTSLCTSKEPHX1 | |
| SCHEMBL6686849 | 0.84 | CTSS (0.48) | CTSSCTSLCTSKEPHX1 | |
| SCHEMBL6685718 | 0.81 | TDP1 (0.48) | CTSSCTSLCTSKEPHX2EPHX1 | |
| SCHEMBL5841440 | 0.80 | CTSS (0.64) | CTSSCTSLCTSKKDM4EALDH1A1 | |
| SCHEMBL5841433 | 0.80 | CTSS (0.64) | CTSSCTSLCTSKKDM4EALDH1A1 | |
| SCHEMBL6685630 | 0.76 | NPC1 (0.51) | CTSSCTSLCTSKEPHX2 | |
| SCHEMBL6686940 | 0.75 | CTSS (0.56) | CTSSCTSLCTSKEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |