Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 13/20 | 0.41 |
| ▸ | CTSL | P07711 | 12/20 | 0.41 |
| ▸ | CTSK | P43235 | 8/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689998 | 0.89 | EPHX1 (0.48) | TDP1L3MBTL1EPHX1 | |
| SCHEMBL6685688 | 0.84 | KIF11 (0.38) | L3MBTL1EPHX1POLBALDH1A1 | |
| SCHEMBL6690874 | 0.82 | TDP1 (0.47) | TDP1L3MBTL1EPHX2EPHX1POLB | |
| SCHEMBL6685642 | 0.81 | CTSS (0.54) | TDP1L3MBTL1EPHX2EPHX1POLB | |
| SCHEMBL6686917 | 0.81 | CTSS (0.54) | TDP1L3MBTL1EPHX2EPHX1POLB | |
| SCHEMBL6690872 | 0.78 | CTSS (0.53) | TDP1L3MBTL1CTSSCTSLCTSK | |
| SCHEMBL6688737 | 0.76 | CTSS (0.47) | TDP1L3MBTL1EPHX2ALDH1A1CTSS | |
| SCHEMBL5500899 | 0.73 | EPHX1 (0.52) | L3MBTL1EPHX1POLBALDH1A1CTSS | |
| SCHEMBL5398975 | 0.73 | FPR2 (0.43) | EPHX1POLBCTSS | |
| SCHEMBL6688717 | 0.72 | SMN1; SMN2 (0.50) | L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |