SCHEMBL6685677

SCHEMBL6685677

NC(=S)C(C(N)=S)(C1CCCCC1)C1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
LMNA P02545 2/20 0.39
MEN1 O00255 1/20 0.39
ALOX12 P18054 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
MGLL Q99685 1/20 0.35
GAA P10253 1/20 0.34
CTSK P43235 1/20 0.33
EPHX1 P07099 1/20 0.32
NOS2 P35228 1/20 0.32
PHGDH O43175 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6896951 1.00 ALDH1A1 (0.39) ALDH1A1LMNAMEN1ALOX12KMT2A
SCHEMBL7078828 0.89 EPHX1 (0.35) ALDH1A1LMNAMEN1ALOX12KMT2A
SCHEMBL7080108 0.76 EPHX1 (0.41) ALDH1A1SMN1; SMN2CYP3A4EPHX1
SCHEMBL3064939 0.76 NOS2 (0.42) ALDH1A1LMNAMEN1ALOX12KMT2A
SCHEMBL29013937 0.74 EPHX1 (0.39) ALDH1A1SMN1; SMN2CYP3A4EPHX1
SCHEMBL27960380 0.72 EPHX1 (0.37) EPHX1NOS2
Hydrochloric Acid SCHEMBL4532340 0.72 EPHX1 (0.38) ALDH1A1SMN1; SMN2CYP3A4EPHX1
Hydrochloric Acid SCHEMBL4532336 0.72 EPHX1 (0.38) ALDH1A1SMN1; SMN2CYP3A4EPHX1
SCHEMBL28465427 0.72 EPHX1 (0.38) ALDH1A1SMN1; SMN2CYP3A4EPHX1
SCHEMBL27844046 0.70 EPHX1 (0.37) ALDH1A1SMN1; SMN2CYP3A4EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed