SCHEMBL6685771

SCHEMBL6685771

C=CCCOC(=O)OC(=O)CCC=C

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.33
ABCC4 O15439 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
FAAH O00519 1/20 0.32
MGLL Q99685 1/20 0.32
TSHR P16473 5/20 0.32
KDM4E B2RXH2 1/20 0.31
TP53 P04637 2/20 0.30
HIF1A Q16665 2/20 0.30
CYP3A4 P08684 2/20 0.30
HSD17B10 Q99714 1/20 0.30
USP2 O75604 1/20 0.30
RECQL P46063 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2137245 0.85 ALDH1A1 (0.41) ALDH1A1LMNAMAPTABCC4CA2
SCHEMBL16236 0.82 ALDH1A1 (0.45) ALDH1A1LMNAMAPTABCC4CA2
SCHEMBL47886 0.79 CA2 (0.42) ALDH1A1LMNAMAPTABCC4CA2
SCHEMBL28841634 0.79 ALDH1A1 (0.37) ALDH1A1LMNAMAPTABCC4FAAH
SCHEMBL11330333 0.78 ALDH1A1 (0.42) ALDH1A1LMNAMAPTABCC4CA2
SCHEMBL8442984 0.76 ABCC4 (0.41) ALDH1A1LMNAMAPTABCC4FAAH
SCHEMBL5439764 0.75 ALDH1A1 (0.43) ALDH1A1LMNAMAPTABCC4FAAH
SCHEMBL5176877 0.74
SCHEMBL1290659 0.74 ALDH1A1 (0.44) ALDH1A1LMNAMAPTABCC4FAAH
SCHEMBL4171918 0.73 FAAH (0.40) ALDH1A1LMNAMAPTABCC4FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004078685-A2 PROCESS FOR THE PRODUCTION OF 3-BUTEN-1-OL EASTMAN CHEMICAL COMPANY (US) 2004-09-16 WO disclosed
US-6790999-B1 CONVERSION OF 3,4-EPOXY-1-BUTENE USING FORMIC ACID WITH CATALYST SYSTEM COMPOSED OF PALLADIUM COMPLEX, TERTIARY PHOSPHINE AND TRIALKYLAMINE EASTMAN CHEMICAL COMPANY 2004-09-14 US disclosed
US-20040171892-A1 PROCESS FOR THE PRODUCTION OF 3-BUTEN-1-OL EASTMAN CHEMICAL COMPANY 2004-09-02 US disclosed