SCHEMBL6685844

SCHEMBL6685844

COc1cc(Cl)ncc1-c1cc(OC(F)F)n(C)n1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.30
ENPP1 P22413 1/20 0.30
HCRTR1 O43613 1/20 0.30
HCRTR2 O43614 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6691871 0.86 KMT2A (0.32) KMT2A
SCHEMBL6690722 0.80 F2RL3 (0.34) KMT2A
SCHEMBL9081646 0.77 AR (0.42)
SCHEMBL6672816 0.77 SCN9A (0.32) PDE10A
SCHEMBL6818668 0.75 PDE4B (0.33)
SCHEMBL6674197 0.73 PDE4B (0.30)
SCHEMBL6671937 0.72 PDE2A (0.31) PDE10A
SCHEMBL6673150 0.72 KMT2A (0.39) HCRTR1HCRTR2KMT2A
SCHEMBL6675401 0.72 NPC1 (0.35) PDE10AKMT2A
SCHEMBL7588842 0.71 L3MBTL1 (0.32) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004035564-A1 PYRIDINE DERIVATIVES USEFUL AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2004-04-29 WO disclosed
WO-2004035563-A1 3-HETEROCYCLYLPYRIDINE DERIVATIVES USEFUL AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2004-04-29 WO disclosed