Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674197 | 0.86 | PDE4B (0.30) | PDE4B | |
| SCHEMBL6671937 | 0.80 | PDE2A (0.31) | CRHR1 | |
| SCHEMBL6284972 | 0.76 | HSD11B1 (0.42) | CRHR1 | |
| SCHEMBL6320670 | 0.75 | KMO (0.36) | — | |
| SCHEMBL6685844 | 0.75 | PDE10A (0.30) | — | |
| SCHEMBL6918490 | 0.75 | CRHR1 (0.33) | CRHR1PDCD1LG2CD274 | |
| SCHEMBL8472019 | 0.74 | KDM4E (0.37) | — | |
| SCHEMBL9081646 | 0.74 | AR (0.42) | — | |
| SCHEMBL6691871 | 0.73 | KMT2A (0.32) | — | |
| SCHEMBL6673150 | 0.72 | KMT2A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004035563-A1 | 3-HETEROCYCLYLPYRIDINE DERIVATIVES USEFUL AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-04-29 | — | — | WO | disclosed |