SCHEMBL6672816

SCHEMBL6672816

COc1cc(Cl)ncc1-c1nn(C)c(OC(F)F)c1Cl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.32
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6674187 0.86 F2RL3 (0.31)
SCHEMBL6671534 0.81 F2RL3 (0.33)
SCHEMBL6295368 0.78 PDE10A (0.33) PDE10A
SCHEMBL7893363 0.77 PDE2A (0.31) PDE10A
SCHEMBL6682122 0.77 RORC (0.30)
SCHEMBL6685844 0.77 PDE10A (0.30) PDE10A
SCHEMBL6674684 0.74 CHRNB2 (0.35) PDE10A
SCHEMBL6918490 0.74 CRHR1 (0.33) SCN9A
SCHEMBL6819087 0.73 PDE1A (0.39)
SCHEMBL8471677 0.73 AMY1A (0.38) PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004035564-A1 PYRIDINE DERIVATIVES USEFUL AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2004-04-29 WO claimed
WO-2004035563-A1 3-HETEROCYCLYLPYRIDINE DERIVATIVES USEFUL AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2004-04-29 WO claimed
WO-2004035564-A1 PYRIDINE DERIVATIVES USEFUL AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2004-04-29 WO disclosed
WO-2004035563-A1 3-HETEROCYCLYLPYRIDINE DERIVATIVES USEFUL AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2004-04-29 WO disclosed