Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5664312 | 1.00 | PTPN5 (0.35) | PTPN5KDM4EMEN1MAPTKMT2A | |
| SCHEMBL5670173 | 0.86 | CYP1A2 (0.33) | KDM4EMEN1MAPTKMT2AGABBR2 | |
| SCHEMBL5670176 | 0.86 | CYP1A2 (0.33) | KDM4EMEN1MAPTKMT2AGABBR2 | |
| SCHEMBL7063106 | 0.76 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL7063102 | 0.76 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL6918142 | 0.75 | GABBR2 (0.59) | GABBR2GABBR1CYP1A2CYP2C9 | |
| SCHEMBL5667902 | 0.72 | SMN1; SMN2 (0.42) | KDM4EMEN1MAPTKMT2AGABBR2 | |
| SCHEMBL5667900 | 0.72 | SMN1; SMN2 (0.42) | KDM4EMEN1MAPTKMT2AGABBR2 | |
| SCHEMBL5667477 | 0.70 | TOP2A (0.45) | KDM4EMEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL5667474 | 0.70 | TOP2A (0.45) | KDM4EMEN1MAPTKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026243-A2 | THERAPEUTIC USES OF LINEAR KETOPHOSPHONATES | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |