Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 2/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.48 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3309709 | 0.83 | TSHR (0.63) | TSHRALDH1A1HSD17B10CDC25BCA12 | |
| SCHEMBL11418791 | 0.83 | TSHR (0.63) | TSHRALDH1A1HSD17B10CDC25BCYP4F2 | |
| SCHEMBL2601348 | 0.83 | TSHR (0.63) | TSHRALDH1A1HSD17B10CDC25BCYP4F2 | |
| SCHEMBL406428 | 0.82 | TSHR (0.74) | TSHRALDH1A1HSD17B10CDC25BCYP4F2 | |
| SCHEMBL4625495 | 0.81 | TSHR (0.61) | TSHRALDH1A1HSD17B10CDC25BCYP4F2 | |
| SCHEMBL2226875 | 0.81 | NR4A2 (0.51) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL23078360 | 0.80 | TSHR (0.59) | TSHRALDH1A1HSD17B10CDC25BCYP4F2 | |
| SCHEMBL9188030 | 0.80 | TSHR (0.59) | TSHRALDH1A1HSD17B10CDC25BCYP4F2 | |
| SCHEMBL22853326 | 0.80 | TSHR (0.59) | TSHRALDH1A1HSD17B10CDC25BCYP4F2 | |
| SCHEMBL22206861 | 0.80 | TSHR (0.59) | TSHRALDH1A1HSD17B10CDC25BCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758453-B2 | One-component reagent for the fluoroalkylation reaction | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-09-12 | — | — | US | disclosed |
| US-20160185691-A1 | One-Component Reagent for the Fluoroalkylation Reaction | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF LLLINOIS (US) | 2016-06-30 | — | — | US | disclosed |
| US-9193648-B2 | Fluoroalkylation methods and reagents | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-11-24 | — | — | US | disclosed |
| US-20130225815-A1 | Fluoroalkylation Methods And Reagents | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-08-29 | — | — | US | disclosed |
| EP-2606048-A1 | FLUOROALKYLATION METHODS AND REAGENTS | The Board of Trustees of the University of Illinois (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012024564-A1 | FLUOROALKYLATION METHODS AND REAGENTS | THE BOARD OF TRUSTESS OF THE UNIVERSITY OF ILLINOIS (US) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225815-A1 | Fluoroalkylation Methods And Reagents | ALK, AFF4, AFF2 | TSHR 331/4885ALDH1A1 1320/4885HSD17B10 4024/4885 |
| US-20160185691-A1 | One-Component Reagent for the Fluoroalkylation Reaction | AOC1, AOC3, AOC2 | TSHR 1993/4885ALDH1A1 167/4885HSD17B10 2483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.