Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 3/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8963683 | 0.98 | MGAM (0.49) | MGAMGAASIMGAM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8963758 | 0.84 | NPC1 (0.49) | MGAMGAASIMGAM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10649427 | 0.82 | MGAM (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL19350089 | 0.81 | CTSS (0.47) | GAAGUSBKMT2AHPGDHSD11B1 | |
| SCHEMBL23758280 | 0.80 | MGAM (0.55) | MGAMGAASIMGAM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8963481 | 0.79 | L3MBTL1 (0.51) | GAAALDH1A1SLC9A1DCUN1D1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8963873 | 0.79 | TRPA1 (0.35) | MGAMGAASIMGAM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1436115 | 0.77 | PIN1 (0.50) | GAAALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL19350009 | 0.76 | CTSS (0.51) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL27762185 | 0.74 | MAPK14 (0.54) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417202-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-12 | — | — | EP | disclosed |
| WO-2002079186-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2002-10-10 | — | — | WO | disclosed |