Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.46 |
| ▸ | CTSL | P07711 | 11/20 | 0.46 |
| ▸ | CTSK | P43235 | 7/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686203 | 0.86 | BMP1 (0.42) | CTSSCTSLCTSKMMP1MMP2 | |
| SCHEMBL6690766 | 0.84 | CTSS (0.44) | CTSSCTSLCTSKMMP1MMP2 | |
| SCHEMBL6686240 | 0.81 | CTSS (0.41) | CTSSCTSLCTSK | |
| SCHEMBL6693432 | 0.81 | CTSS (0.41) | CTSSCTSLCTSKMMP1MMP2 | |
| SCHEMBL5842372 | 0.80 | CTSS (0.66) | CTSSCTSLCTSK | |
| SCHEMBL5842376 | 0.80 | CTSS (0.66) | CTSSCTSLCTSK | |
| SCHEMBL6686187 | 0.80 | CTSL (0.46) | CTSSCTSLCTSK | |
| SCHEMBL5497651 | 0.80 | CTSS (0.40) | CTSSCTSLCTSK | |
| SCHEMBL6690633 | 0.79 | USP30 (0.40) | CTSSCTSLCTSKMMP1 | |
| SCHEMBL6696331 | 0.79 | CTSS (0.37) | CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |