Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.72 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.72 |
| ▸ | DRD2 | P14416 | 4/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | GOT1 | P17174 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113532 | 0.94 | DRD2 (0.65) | HTR6ADRB1DRD2DRD3DRD4 | |
| SCHEMBL1012802 | 0.85 | ADRB1 (1.00) | HTR6ADRB1DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL4662618 | 0.84 | ADRB1 (0.97) | HTR6ADRB1DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL6730585 | 0.84 | ADRB1 (0.97) | HTR6ADRB1DRD2DRD3DRD4 | |
| SCHEMBL7732059 | 0.80 | DRD2 (0.69) | HTR6ADRB1DRD2DRD3DRD4 | |
| SCHEMBL7534110 | 0.80 | DRD2 (0.65) | HTR6ADRB1DRD2DRD3DRD4 | |
| SCHEMBL29046800 | 0.78 | DRD2 (0.66) | HTR6ADRB1DRD2DRD3DRD4 | |
| SCHEMBL23102103 | 0.77 | DRD2 (0.68) | HTR6ADRB1DRD2DRD3DRD4 | |
| SCHEMBL791195 | 0.77 | DRD2 (0.61) | HTR6ADRB1DRD2DRD3DRD4 | |
| SCHEMBL17817484 | 0.76 | DRD2 (0.60) | HTR6ADRB1DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399434-A1 | NOVEL INDOLE DERIVATIVES | H. Lundbeck A/S (DK) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003002552-A1 | NOVEL INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2003-01-09 | — | — | WO | disclosed |