Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.69 |
| ▸ | DRD3 | P35462 | 3/20 | 0.69 |
| ▸ | DRD4 | P21917 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.60 |
| ▸ | HTR6 | P50406 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | GOT1 | P17174 | 7/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29046800 | 0.92 | DRD2 (0.66) | DRD2DRD3DRD4GAAMAPT | |
| SCHEMBL7534110 | 0.86 | DRD2 (0.65) | DRD2DRD3DRD4GAAMAPT | |
| SCHEMBL5113532 | 0.86 | DRD2 (0.65) | DRD2DRD3DRD4GAAMAPT | |
| SCHEMBL23102103 | 0.82 | DRD2 (0.68) | DRD2DRD3DRD4GAAMAPT | |
| SCHEMBL791195 | 0.82 | DRD2 (0.61) | DRD2DRD3DRD4GAAMAPT | |
| SCHEMBL2161609 | 0.82 | DRD4 (1.00) | DRD2DRD3DRD4GAAMAPT | |
| SCHEMBL17817484 | 0.81 | DRD2 (0.60) | DRD2DRD3DRD4GAAMAPT | |
| SCHEMBL4306478 | 0.80 | ADRB1 (0.69) | DRD2DRD3DRD4GAAMAPT | |
| SCHEMBL6686430 | 0.80 | HTR6 (0.72) | DRD2DRD3DRD4GAAMAPT | |
| SCHEMBL2161623 | 0.80 | DRD2 (0.58) | DRD2DRD3DRD4GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554145-A | Aralkyl-4- (1H) indolylpiperazine derivative, preparation method and application thereof | 江苏恩华药业股份有限公司 | 2023-08-08 | — | — | CN | disclosed |
| US-6399614-B1 | TREATING NEUROMUSCULAR DYSFUNCTION OF LOWER URINARY TRACT VIA PERIPHERAL OR CENTRAL NERVOUS SYSTEM; SEROTONIN RECEPTOR ANTAGONIST | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-04 | — | — | US | disclosed |