Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688811 | 0.88 | MAPT (0.47) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6689426 | 0.88 | MAPT (0.51) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6688567 | 0.80 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6687401 | 0.69 | MAPT (0.55) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6690846 | 0.68 | RAB9A (0.60) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL28519664 | 0.67 | SMN1; SMN2 (0.67) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL29506272 | 0.67 | GAA (0.70) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL28391228 | 0.66 | ALDH1A1 (0.47) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL29506305 | 0.66 | ALDH1A1 (0.47) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL15246754 | 0.62 | RAB9A (0.61) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |