Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536567 | 0.82 | PARP1 (0.34) | — | |
| SCHEMBL7729865 | 0.75 | SLC6A2 (0.33) | ALDH1A1SLC6A4KIF11SLC6A3SLC6A2 | |
| SCHEMBL6689781 | 0.71 | OPRM1 (0.32) | OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL10905443 | 0.65 | P2RX4 (0.43) | ALDH1A1KIF11OPRM1OPRL1 | |
| SCHEMBL11856621 | 0.63 | MAOA (0.36) | KDM1A | |
| SCHEMBL31442138 | 0.63 | HDAC9 (0.35) | OPRM1OPRL1OPRK1 | |
| SCHEMBL29223962 | 0.63 | CA1 (0.33) | — | |
| SCHEMBL6689248 | 0.63 | HDAC9 (0.33) | ALDH1A1KIF11OPRM1 | |
| SCHEMBL8133774 | 0.62 | PRCP (0.34) | — | |
| SCHEMBL29921089 | 0.62 | PARP1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085568-A2 | PHOTOCHROMIC ARTICLES WITH REDUCED TEMPERATURE DEPENDENCY AND METHODS FOR PREPARATION | TRANSITIONS OPTICAL, INC. (US) | 2004-10-07 | — | — | WO | disclosed |