Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689248 | 0.90 | HDAC9 (0.33) | OPRM1HDAC9 | |
| SCHEMBL5072171 | 0.88 | — | — | |
| SCHEMBL6536500 | 0.85 | ATM (0.34) | OPRM1OPRL1 | |
| SCHEMBL6536567 | 0.84 | PARP1 (0.34) | HDAC9 | |
| SCHEMBL6536806 | 0.80 | — | — | |
| SCHEMBL9546931 | 0.80 | MAOA (0.36) | — | |
| SCHEMBL7729865 | 0.76 | SLC6A2 (0.33) | — | |
| SCHEMBL6689370 | 0.76 | MAPT (0.35) | — | |
| SCHEMBL4239575 | 0.74 | HPGD (0.40) | — | |
| SCHEMBL8085651 | 0.72 | PDK2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085568-A2 | PHOTOCHROMIC ARTICLES WITH REDUCED TEMPERATURE DEPENDENCY AND METHODS FOR PREPARATION | TRANSITIONS OPTICAL, INC. (US) | 2004-10-07 | — | — | WO | claimed |
| WO-2004085568-A2 | PHOTOCHROMIC ARTICLES WITH REDUCED TEMPERATURE DEPENDENCY AND METHODS FOR PREPARATION | TRANSITIONS OPTICAL, INC. (US) | 2004-10-07 | — | — | WO | disclosed |