Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689781 | 0.90 | OPRM1 (0.32) | HDAC9OPRM1 | |
| SCHEMBL6536500 | 0.87 | ATM (0.34) | OPRM1ALDH1A1CHRM5KIF11 | |
| SCHEMBL5072171 | 0.84 | — | — | |
| SCHEMBL9546931 | 0.81 | MAOA (0.36) | MEN1KMT2A | |
| SCHEMBL8085651 | 0.81 | PDK2 (0.35) | MEN1KMT2ACHRM5 | |
| SCHEMBL6536806 | 0.77 | — | — | |
| SCHEMBL6536567 | 0.73 | PARP1 (0.34) | HDAC9 | |
| SCHEMBL4239575 | 0.71 | HPGD (0.40) | MEN1ALDH1A1KMT2A | |
| SCHEMBL6689370 | 0.70 | MAPT (0.35) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7455420 | 0.70 | ACHE (0.37) | OPRM1ALDH1A1CHRM5KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085568-A2 | PHOTOCHROMIC ARTICLES WITH REDUCED TEMPERATURE DEPENDENCY AND METHODS FOR PREPARATION | TRANSITIONS OPTICAL, INC. (US) | 2004-10-07 | — | — | WO | disclosed |