Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 3/20 | 0.46 |
| ▸ | CTSS | P25774 | 7/20 | 0.44 |
| ▸ | REN | P00797 | 4/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687349 | 0.94 | CTSL (0.49) | CTSLCTSBCTSSCTSK | |
| SCHEMBL6690009 | 0.90 | CTSS (0.46) | CTSLCTSBCTSSRENCTSK | |
| SCHEMBL6691400 | 0.86 | CTSL (0.44) | CTSLCTSBCTSSCTSK | |
| SCHEMBL6693488 | 0.85 | CTSS (0.61) | CTSLCTSSCTSK | |
| SCHEMBL6687004 | 0.85 | SYK (0.44) | CTSLCTSKKLK7KLK5 | |
| SCHEMBL6688121 | 0.81 | CTSL (0.47) | CTSLCTSBCTSSCTSK | |
| SCHEMBL6693567 | 0.81 | CTSS (0.68) | CTSLCTSSCTSK | |
| SCHEMBL6687234 | 0.80 | CTSS (0.44) | CTSLCTSBCTSSRENCTSK | |
| SCHEMBL4798183 | 0.80 | CTSS (0.68) | CTSLCTSSCTSK | |
| SCHEMBL4798170 | 0.80 | CTSS (0.68) | CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |