Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688121 | 0.93 | CTSL (0.47) | CTSLCTSBCTSSCTSKIDO1 | |
| SCHEMBL6687004 | 0.92 | SYK (0.44) | CTSLMMP8CTSKSYKIDO1 | |
| SCHEMBL6687234 | 0.87 | CTSS (0.44) | CTSLCTSBCTSSCTSKIDO1 | |
| SCHEMBL6688070 | 0.86 | CTSL (0.46) | CTSLCTSBCTSSCTSK | |
| SCHEMBL6687349 | 0.83 | CTSL (0.49) | CTSLCTSBCTSSCTSK | |
| SCHEMBL6690545 | 0.81 | CTSS (0.53) | CTSLCTSSCTSK | |
| SCHEMBL6697383 | 0.80 | CTSS (0.46) | CTSLCTSSCTSK | |
| SCHEMBL6690009 | 0.79 | CTSS (0.46) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4799969 | 0.77 | CTSS (0.59) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4799962 | 0.77 | CTSS (0.59) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |