Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691400 | 0.92 | CTSL (0.44) | SYKCTSLIDO1TDO2MMP8 | |
| SCHEMBL6688070 | 0.85 | CTSL (0.46) | CTSLCTSKKLK7KLK5 | |
| SCHEMBL6688121 | 0.83 | CTSL (0.47) | CTSLIDO1TDO2CTSKCASP1 | |
| SCHEMBL6687349 | 0.81 | CTSL (0.49) | CTSLCTSKCASP1 | |
| SCHEMBL6690009 | 0.77 | CTSS (0.46) | CTSLCTSK | |
| SCHEMBL8286606 | 0.74 | IDO1 (0.53) | CTSLIDO1TDO2CCKBR | |
| SCHEMBL6690545 | 0.73 | CTSS (0.53) | CTSLCTSK | |
| SCHEMBL6697383 | 0.73 | CTSS (0.46) | CTSLCTSK | |
| SCHEMBL25256638 | 0.73 | SYK (0.62) | SYKCTSLCTSKITGB3ITGA2B | |
| SCHEMBL7360205 | 0.73 | CTRB1 (0.62) | SYKCTSLCTSKITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004112709-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-12-29 | — | — | WO | disclosed |
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |