Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685578 | 0.93 | FOLH1 (0.41) | FOLH1CASRGAAHDAC1HDAC6 | |
| SCHEMBL6681620 | 0.90 | FOLH1 (0.43) | FOLH1CASRC3AR1CCKBRHTT | |
| SCHEMBL6690573 | 0.90 | HDAC1 (0.40) | FOLH1CASRGAAHDAC1HDAC6 | |
| SCHEMBL6681809 | 0.89 | FOLH1 (0.39) | FOLH1CASRC3AR1CCKBRHTT | |
| SCHEMBL6685296 | 0.85 | FOLH1 (0.38) | FOLH1CASRC3AR1CCKBRHTT | |
| SCHEMBL6683363 | 0.83 | FOLH1 (0.41) | FOLH1CASRC3AR1CCKBR | |
| SCHEMBL6682711 | 0.80 | CXCR4 (0.40) | FOLH1CASRHDAC1MEN1KMT2A | |
| SCHEMBL6018132 | 0.79 | HDAC1 (0.41) | GAAHDAC1HDAC6MEN1KMT2A | |
| SCHEMBL6018574 | 0.78 | CXCR4 (0.51) | FOLH1CASRHDAC1KMT2A | |
| SCHEMBL6019671 | 0.78 | CXCR4 (0.49) | FOLH1CASRGAAHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389460-A1 | CXCR4-ANTAGONISTIC DRUGS COMPRISING NITROGEN-CONTAINING COMPOUND | Kureha Chemical Industry Co., Ltd. (JP) | 2004-02-18 | — | — | EP | disclosed |
| EP-1273571-A1 | NITROGENOUS COMPOUNDS AND ANTIVIRAL DRUGS CONTAINING THE SAME | Kureha Chemical Industry Co., Ltd. (JP) | 2003-01-08 | — | — | EP | disclosed |