Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691162 | 0.96 | TSPO (0.44) | TSPOPLA2G2AFABP4L3MBTL1 | |
| SCHEMBL6691723 | 0.93 | TSPO (0.44) | TSPOPLA2G2AHTR6FABP4 | |
| SCHEMBL6689210 | 0.87 | TSPO (0.43) | TSPOPLA2G2AFABP4L3MBTL1 | |
| SCHEMBL6688729 | 0.86 | TSPO (0.43) | TSPOPLA2G2AKDM4EHTR6FABP4 | |
| SCHEMBL6691740 | 0.86 | PLA2G2A (0.44) | TSPOPLA2G2AHTR6 | |
| SCHEMBL6697582 | 0.85 | PLA2G2A (0.44) | TSPOPLA2G2AHTR6FABP4 | |
| SCHEMBL27844993 | 0.85 | FABP4 (0.37) | TSPOHTR6FABP4 | |
| SCHEMBL818609 | 0.84 | PLA2G2A (0.47) | PLA2G2A | |
| SCHEMBL29862385 | 0.84 | PLA2G2A (0.47) | PLA2G2A | |
| SCHEMBL27594802 | 0.84 | FABP4 (0.36) | TSPOPLA2G2AFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950657-B1 | Substituted carbazoles, process for their preparation and their use as sPLA2 inhibitors | LILLY CO ELI (US) | 2004-07-14 | — | — | EP | disclosed |