Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | TNF | P01375 | 2/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5740679 | 0.99 | ALDH1A1 (0.40) | ABCC1ABCC2MEN1KMT2ARAB9A | |
| SCHEMBL5756243 | 0.80 | TDP1 (0.34) | MEN1KMT2ARAB9ATDP1KDM4E | |
| SCHEMBL5756239 | 0.80 | TNF (0.34) | ABCC1ABCC2MEN1KMT2ARAB9A | |
| SCHEMBL5756237 | 0.80 | TDP1 (0.34) | MEN1KMT2ARAB9ATDP1KDM4E | |
| SCHEMBL6689646 | 0.80 | PTGS2 (0.39) | MEN1KMT2ATDP1NOD1L3MBTL1 | |
| SCHEMBL5741839 | 0.79 | RXRA (0.37) | RAB9AFABP4NPC1 | |
| SCHEMBL5740682 | 0.79 | PTGS2 (0.38) | MEN1KMT2ARAB9ATDP1KDM4E | |
| SCHEMBL28456554 | 0.78 | TTR (0.49) | RAB9ATDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL5741304 | 0.77 | HSD17B10 (0.44) | MEN1KMT2ARAB9ATNFNOD1 | |
| SCHEMBL5739664 | 0.76 | PTGER4 (0.42) | MEN1KMT2ARAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406891-A1 | THIOCHROMENONES USED TO COMBAT PAINFUL CONDITIONS AND NEURODEGENERATIVE DISEASES | Bayer HealthCare AG (DE) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003053955-A1 | THIOCHROMENONES USED TO COMBAT PAINFUL CONDITIONS AND NEURODEGENERATIVE DISEASES | BAYER HEALTHCARE AG (DE) | 2003-07-03 | — | — | WO | disclosed |