Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860949 | 1.00 | ALDH1A1 (0.55) | ALDH1A1LMNATP53CYP3A4KDM4E | |
| SCHEMBL9860997 | 0.94 | ALDH1A1 (0.57) | ALDH1A1LMNATP53CYP3A4KDM4E | |
| SCHEMBL9860994 | 0.94 | ALDH1A1 (0.57) | ALDH1A1LMNATP53CYP3A4KDM4E | |
| SCHEMBL29020605 | 0.87 | ALDH1A1 (0.50) | ALDH1A1LMNATP53CYP3A4KDM4E | |
| SCHEMBL15690177 | 0.82 | TP53 (0.59) | ALDH1A1LMNATP53CYP3A4KDM4E | |
| SCHEMBL8027229 | 0.82 | CHRNB2 (0.49) | ALDH1A1LMNATP53CYP3A4KDM4E | |
| SCHEMBL8024628 | 0.82 | CHRNB2 (0.49) | ALDH1A1LMNATP53CYP3A4KDM4E | |
| SCHEMBL6689787 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL15688654 | 0.82 | TP53 (0.59) | ALDH1A1LMNATP53CYP3A4KDM4E | |
| SCHEMBL23419402 | 0.81 | THRB (0.58) | ALDH1A1KDM4EMAPTHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165769-B1 | POLYFUNCTIONAL STYRYLOXY COMPOUNDS AND METHOD OF FORMING A CROSS-LINKED POLYMER | LOCTITE (IRELAND) Ltd. (IE) | 1991-08-21 | — | — | EP | claimed |
| EP-0165769-B1 | POLYFUNCTIONAL STYRYLOXY COMPOUNDS AND METHOD OF FORMING A CROSS-LINKED POLYMER | LOCTITE (IRELAND) Ltd. (IE) | 1991-08-21 | — | — | EP | disclosed |