Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528484 | 0.86 | CTSS (0.55) | MEN1KMT2AALDH1A1CTSSCTSK | |
| SCHEMBL5841881 | 0.78 | CTSK (0.60) | CTSSCTSKCTSL | |
| SCHEMBL30921399 | 0.77 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1EPHX1LMNA | |
| SCHEMBL375858 | 0.76 | LMNA (0.73) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| Water SCHEMBL8101580 | 0.75 | LMNA (0.71) | MEN1KMT2ACTSSCTSKCTSL | |
| Hydrochloric Acid SCHEMBL3259897 | 0.75 | LMNA (0.71) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4974687 | 0.73 | LMNA (0.52) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6647029 | 0.73 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1EPHX1CTSS | |
| SCHEMBL10644047 | 0.73 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1EPHX1CTSS | |
| SCHEMBL28688698 | 0.73 | CYP3A4 (0.56) | MEN1KMT2AALDH1A1EPHX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |