Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.33 |
| ▸ | GLRB | P48167 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882183 | 0.80 | HPGDS (0.41) | HPGDSLTA4HBRD4ADORA2AADORA1 | |
| SCHEMBL100765 | 0.80 | HPGDS (0.46) | HPGDSLTA4HBRD4ADORA2AADORA1 | |
| SCHEMBL17701262 | 0.78 | HPGDS (0.40) | HPGDSLTA4HBRD4ADORA2AADORA1 | |
| SCHEMBL15627195 | 0.77 | SMN1; SMN2 (0.41) | HPGDSLTA4HADORA2AADORA1KDM4E | |
| SCHEMBL13114685 | 0.77 | HPGDS (0.47) | HPGDSLTA4HBRD4ADORA2AADORA1 | |
| SCHEMBL17701187 | 0.73 | HPGDS (0.37) | HPGDSLTA4H | |
| SCHEMBL8363957 | 0.73 | HPGDS (0.41) | HPGDSLTA4HBRD4ADORA2AADORA1 | |
| SCHEMBL30066184 | 0.73 | HPGDS (0.41) | HPGDSLTA4HBRD4ADORA2AADORA1 | |
| SCHEMBL27176352 | 0.73 | HPGDS (0.41) | HPGDSLTA4HBRD4ADORA2AADORA1 | |
| SCHEMBL15629752 | 0.72 | SMN1; SMN2 (0.41) | HPGDSLTA4HKDM4ENPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959884-A | 6-heterocyclic imidazo [1, 2-alpha ] pyridine-2-carboxamide derivatives, preparation and therapeutic use thereof | SANOFI AVENTIS | 2011-01-26 | — | — | CN | claimed |
| CN-101553233-A | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases | DECIPHERA PHARMACEUTICALS LLC (US) | 2009-10-07 | — | — | CN | claimed |
| CN-101553232-A | Kinase inhibitors useful for the treatment of proliferative diseases | DECIPHERA PHARMACEUTICALS LLC (US) | 2009-10-07 | — | — | CN | claimed |
| CN-101516379-A | Kinase inhibitors useful for the treatment of proliferative diseases | DECIPHERA PHARMACEUTICALS LLC (US) | 2009-08-26 | — | — | CN | claimed |
| CN-1222527-C | Pyridine and pyrimidine derivatives and their use as inhibitors of cytokines mediating diseases | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | claimed |
| CN-1660849-A | Pyridine and pyrimidine derivatives and their use as inhibitors of cytokines mediating diseases | ASTRAZENECA AB (SE) | 2005-08-31 | — | — | CN | claimed |
| CN-1351604-A | Pyridine and pyrimidine derivatives and their use as inhibitors of cytokines mediating diseases | ASTRAZENECA AB (SE) | 2002-05-29 | — | — | CN | claimed |
| US-20250289818-A1 | HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF CANCER | TOLREMO THERAPEUTICS AG (CH) | 2025-09-18 | — | — | US | disclosed |
| CN-116867373-A | Herbicidal composition | 日本曹达株式会社 | 2023-10-10 | — | — | CN | disclosed |
| US-20230067929-A1 | HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF CANCER | TOLREMO THERAPEUTICS AG (CH) | 2023-03-02 | — | — | US | disclosed |
| CN-109561684-A | The pyrimidine compound of weeding | 巴斯夫欧洲公司 | 2019-04-02 | — | — | CN | disclosed |
| US-9812315-B2 | Treating solution for electronic parts, and process for producing electronic parts | FINE POLYMERS CORPORATION (JP) | 2017-11-07 | — | — | US | disclosed |
| US-20150279654-A1 | TREATING SOLUTION FOR ELECTRONIC PARTS, AND PROCESS FOR PRODUCING ELECTRONIC PARTS | FINE POLYMERS CORPORATION (JP) | 2015-10-01 | — | — | US | disclosed |
| CN-1360582-A | Quinazoline derivs. | ASTRAZENECA UK LTD (GB) | 2002-07-24 | — | — | CN | disclosed |
| CN-1351604-A | Pyridine and pyrimidine derivatives and their use as inhibitors of cytokines mediating diseases | ASTRAZENECA AB (SE) | 2002-05-29 | — | — | CN | disclosed |
| CN-1082503-C | Process for the preparation of methylamides of alpha-methoxyiminocarboxylic acids and intermediates therefor | BASF AG (DE) | 2002-04-10 | — | — | CN | disclosed |
| CN-1272109-A | Method for producing isoxazolidinedione compound | JAPAN TOBACCO INC (JP) | 2000-11-01 | — | — | CN | disclosed |
| CN-1233241-A | Propionic acid derivatives and uses thereof | JAPAN TOBACCO INC (JP) | 1999-10-27 | — | — | CN | disclosed |
| CN-1200117-A | Phenylacetic acids, processes for their preparation and agents containing them | BASF AG (DE) | 1998-11-25 | — | — | CN | disclosed |
| CN-1153509-A | Process for the preparation of methylamides of alpha-methoxyiminocarboxylic acids and intermediates therefor | BASF AG (DE) | 1997-07-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250289818-A1 | HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF CANCER | SLC10A1, SLC6A6, SLC10A6 | HPGDS 1558/4885LTA4H 2010/4885BRD4 3981/4885 |
| US-20230067929-A1 | HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF CANCER | SLC10A1, SLC6A6, SLC10A6 | HPGDS 2109/4885LTA4H 2419/4885BRD4 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.