SCHEMBL6690189

SCHEMBL6690189

Cc1ccc(S(=O)(=O)Oc2cc(C)cs2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.46
CA12 O43570 3/20 0.46
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
GAA P10253 3/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
PTGS2 P35354 1/20 0.41
CYP1A2 P05177 1/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
GFER P55789 1/20 0.40
PPARG P37231 1/20 0.40
CA1 P00915 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6938283 0.77 KEAP1 (0.45) CA2CA12KMT2AMEN1KEAP1
SCHEMBL5083041 0.75 MEN1 (0.58) CA2CA12KMT2AMEN1KEAP1
SCHEMBL4126086 0.72 MEN1 (0.60) CA2CA12KMT2AMEN1GAA
SCHEMBL9852204 0.72 MEN1 (0.60) CA2CA12KMT2AMEN1GAA
SCHEMBL18179825 0.72 MEN1 (0.60) CA2CA12KMT2AMEN1GAA
SCHEMBL6939225 0.72 MEN1 (0.55) CA2CA12KMT2AMEN1KEAP1
Iodide SCHEMBL22068772 0.71 CA2 (0.59) CA2CA12KMT2AMEN1SMN1; SMN2
SCHEMBL28584784 0.70 RAPGEF4 (0.53) CA2CA12KMT2AMEN1KEAP1
SCHEMBL13924689 0.70 ALDH1A1 (0.55) CA2CA12KMT2AMEN1SMN1; SMN2
SCHEMBL6937931 0.70 CA12 (0.48) CA2CA12KMT2AMEN1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0987567-B1 A sulfur-containing (thio)ether (co)polymer and a use thereof MITSUI CHEMICALS INC (JP) 2004-04-07 EP disclosed
US-6320020-B1 POLYMER OR COPOLYMER CONTAINING A SULFUR ATOM WHOSE PRINCIPAL BACKBONE COMPRISES ETHER AND/OR THIOETHER BONDS; OPTICAL DISK SUBSTRATE; A LIQUID-CRYSTAL PLASTIC SUBSTRATE; VARIOUS OPTICAL LENSES INCLUDING AN EYEGLASS; AND AN LED SEALING COAT. MITSUI CHEMICALS, INC. (JP) 2001-11-20 US disclosed
EP-0987567-A1 A sulfur-containing (thio)ether (co)polymer and a use thereof Mitsui Chemicals, Inc. (JP) 2000-03-22 EP disclosed