Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694242 | 0.88 | ALDH1A1 (0.56) | HPGDALDH1A1TDP1DRD2DRD4 | |
| SCHEMBL6690259 | 0.85 | ALDH1A1 (0.53) | HPGDALDH1A1TDP1DRD2DRD4 | |
| SCHEMBL6691797 | 0.81 | ALDH1A1 (0.60) | HPGDALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL6689079 | 0.78 | CYP1A2 (0.40) | HPGDALDH1A1TDP1RPS6KA2DRD2 | |
| SCHEMBL80270 | 0.76 | ALDH1A1 (1.00) | HPGDALDH1A1TDP1DRD2DRD3 | |
| SCHEMBL29658287 | 0.76 | ALDH1A1 (1.00) | HPGDALDH1A1TDP1DRD2DRD3 | |
| SCHEMBL6690657 | 0.75 | HSP90AA1 (0.43) | HPGDALDH1A1MEN1HSP90AA1KMT2A | |
| SCHEMBL6697802 | 0.75 | HSP90AA1 (0.39) | HPGDALDH1A1TDP1MEN1HSP90AA1 | |
| SCHEMBL10714830 | 0.75 | ALDH1A1 (0.97) | HPGDALDH1A1TDP1DRD2DRD3 | |
| SCHEMBL6901949 | 0.75 | HSP90AA1 (0.48) | HPGDALDH1A1TDP1MEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463500-A1 | USE OF COX-2 INHIBITORS IN COMBINATION WITH ANTIVIRAL AGENTS FOR THE TREATMENT OF PAPILLOMA VIRUS INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 2004-10-06 | — | — | EP | claimed |
| WO-2003059347-A1 | USE OF COX-2 INHIBITORS IN COMBINATION WITH ANTIVIRAL AGENTS FOR THE TREATMENT OF PAPILLOMA VIRUS INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-24 | — | — | WO | claimed |
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0945482-B1 | Rubber composition for tire tread and pneumatic tire using same | BRIDGESTONE CORP (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-0890605-B1 | Pneumatic tire | BRIDGESTONE CORP (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-1277795-A2 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-20020010283-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2002-01-24 | — | — | US | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| US-6242522-B1 | A DIENE BASED SYNTHETIC RUBBER OR NATURAL RUBBER BLEND CONTAINING BUTADIENE-STYRENE RUBBER, ALUMINUM HYDROXIDE POWDER, SILICA POWDER, CARBON BLACK; LOW FUEL CONSUMPTION AND WEAR RESISTANCE; IMPROVED GRIPPING IN WET AND COLD SITUATIONS | BRIDGESTONE CORPORATION (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6186204-B1 | EXCELLENT STABILITY AND CONTROLLABILITY ON WET ROADS OR A COMBINATION OF STABILITY AND CONTROLLABILITY ON WET ROADS AND EXCELLENT COMFORT OF RIDE EVEN WHEN A VEHICLE IS VIBRATING THROUGHOUT THE LIFE OF THE PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0948029-A2 | High pressure discharge lamp | NGK INSULATORS, LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| EP-0890605-A2 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |
| EP-0854168-A1 | Rubber composition | Bridgestone Corporation (JP) | 1998-07-22 | — | — | EP | disclosed |