Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | PNMT | P11086 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6406061 | 0.83 | LMNA (0.36) | ALDH1A1LMNACYP3A4PNMTCYP1A2 | |
| SCHEMBL19998489 | 0.81 | LMNA (0.38) | LMNACYP3A4CYP1A2TRPA1CHRM1 | |
| SCHEMBL10341249 | 0.80 | TSHR (0.37) | ALDH1A1LMNACYP3A4PNMTCYP1A2 | |
| SCHEMBL13038361 | 0.79 | LMNA (0.39) | ALDH1A1LMNACYP3A4PNMTCYP1A2 | |
| SCHEMBL10341257 | 0.78 | LMNA (0.36) | ALDH1A1LMNACYP3A4PNMTCYP1A2 | |
| SCHEMBL12992602 | 0.77 | LMNA (0.38) | ALDH1A1LMNACYP3A4PNMTCYP1A2 | |
| SCHEMBL117623 | 0.77 | CYP3A4 (0.40) | ALDH1A1LMNACYP3A4CYP1A2TP53 | |
| SCHEMBL10083916 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CYP3A4CYP1A2TP53TSHR | |
| SCHEMBL9879909 | 0.75 | GABRA1 (0.39) | ALDH1A1LMNACYP3A4CYP1A2TP53 | |
| SCHEMBL20668552 | 0.74 | LMNA (0.35) | ALDH1A1LMNATP53HTTTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9193667-B2 | Process for the selective meta-chlorination of alkylanilines | LONZA LTD. (CH) | 2015-11-24 | — | — | US | disclosed |
| US-20130338400-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | LONZA LTD. (CH) | 2013-12-19 | — | — | US | disclosed |
| EP-2606028-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | Lonza Ltd (CH) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012022460-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | LONZA LTD (CH) | 2012-02-23 | — | — | WO | disclosed |
| US-4950792-A | CHAIN LENGTHENING, CROSSLINKING AGENT FOR POLYURETHANES | LONZA LTD. (CH) | 1990-08-21 | — | — | US | disclosed |
| EP-0220641-B1 | SUBSTITUTED P,P'-METHYLENE-BIS-ANILINES | LONZA AG (CH) | 1990-02-28 | — | — | EP | disclosed |
| EP-0220641-A1 | Substituted p,p'-methylene-bis-anilines | LONZA AG (CH) | 1987-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338400-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | CLIC4, CLIC1, NPM1 | ALDH1A1 2408/4885LMNA 4483/4885CYP3A4 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.