Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31278320 | 1.00 | CYP19A1 (0.51) | CYP19A1CES1ACHEKDM4EALDH1A1 | |
| SCHEMBL12500873 | 0.89 | CYP2A6 (0.50) | CYP19A1CES1ACHEKDM4EALDH1A1 | |
| SCHEMBL13039620 | 0.79 | DRD2 (0.56) | CYP19A1CES1ACHECYP2A6MAOA | |
| SCHEMBL1240296 | 0.79 | ACHE (0.59) | CYP19A1CES1ACHEKDM4EMAPT | |
| SCHEMBL29865183 | 0.79 | ACHE (0.59) | CYP19A1CES1ACHEKDM4EMAPT | |
| SCHEMBL30707960 | 0.78 | CYP19A1 (0.53) | CYP19A1CES1ACHEKDM4EALDH1A1 | |
| SCHEMBL1094690 | 0.78 | CYP19A1 (0.53) | CYP19A1CES1ACHEKDM4EALDH1A1 | |
| SCHEMBL1332811 | 0.78 | CYP19A1 (0.53) | CYP19A1CES1ACHEKDM4EALDH1A1 | |
| SCHEMBL11819054 | 0.78 | CYP19A1 (0.53) | CYP19A1CES1ACHEKDM4EALDH1A1 | |
| SCHEMBL385513 | 0.78 | CYP19A1 (0.53) | CYP19A1CES1ACHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117326923-A | Fluorine-containing dihydronaphthalenone derivative and preparation method and application thereof | 上海应用技术大学 | 2024-01-02 | — | — | CN | claimed |
| WO-2025118034-A1 | COMPOUNDS ACTIVE AT THE SEROTONERGIC 5-HT2A RECEPTOR | Psylo Pty Ltd (AU) | 2025-06-12 | — | — | WO | disclosed |
| CN-117326923-A | Fluorine-containing dihydronaphthalenone derivative and preparation method and application thereof | 上海应用技术大学 | 2024-01-02 | — | — | CN | disclosed |
| CN-117126126-A | Method for asymmetrically synthesizing adjacent halohydrin compound | 凯特立斯（深圳）科技有限公司 | 2023-11-28 | — | — | CN | disclosed |
| WO-2022268066-A1 | PROTEIN DEGRADATION AGENT | 苏州开拓药业股份有限公司 | 2022-12-29 | — | — | WO | disclosed |
| CN-112321398-B | Method for synthesizing alpha-fluorinated ketone by hydrazonating aliphatic chain monoketone | 中山大学 | 2021-11-23 | — | — | CN | disclosed |
| WO-2021060276-A1 | FLUORINATING AGENT AND METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUNDS | ＡＧＣ株式会社 | 2021-04-01 | — | — | WO | disclosed |
| EP-3016931-B1 | A NOVEL PROCESS FOR THE PREPARATION OF TETRALIN AND NAPHTHALENE DERIVATIVES | PHARMATHEN SA (GR) | 2021-02-24 | — | — | EP | disclosed |
| CN-112321398-A | Method for synthesizing alpha-fluorinated ketone by hydrazonating aliphatic chain monoketone | 中山大学 | 2021-02-05 | — | — | CN | disclosed |
| CN-109912397-A | One kind is together with difluoro substituted-tetrahydro naphthalene ketone compounds and preparation method thereof | 上海应用技术大学 | 2019-06-21 | — | — | CN | disclosed |
| US-20140018538-A1 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-01-16 | — | — | US | disclosed |
| EP-2606056-A2 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | President and Fellows of Harvard College (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012024604-A2 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-23 | — | — | WO | disclosed |
| WO-2012024604-A2 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-23 | — | — | WO | disclosed |
| CN-100422181-C | [1,8] naphthyridin-2-ones and related compounds for the treatment of schizophrenia | WARNER LAMBERT CO (US) | 2008-10-01 | — | — | CN | disclosed |
| CN-1839134-A | [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia | WARNER LAMBERT CO (US) | 2006-09-27 | — | — | CN | disclosed |
| US-5243080-A | Ether and ester compounds | ALLIEDSIGNAL INC. (US) | 1993-09-07 | — | — | US | disclosed |
| US-5162587-A | METHOD FOR FLUORINATING BY USING N-FLUOROPYRIDINIUM PYRIDINE HEPTAFLUORODIBORATE | ALLIED-SIGNAL INC. | 1992-11-10 | — | — | US | disclosed |
| WO-1992012983-A1 | A METHOD OF FLUORINATING BY USING N-FLUOROPYRIDINIUM PYRIDINE HEPTAFLUORODIBORATE | ALLIED-SIGNAL INC. (US) | 1992-08-06 | — | — | WO | disclosed |
| US-5086190-A | Heating and reacting androstadienes with the complexes in solvent | ALLIED-SIGNAL INC. (US) | 1992-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018538-A1 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | NECTIN4, FIS1, DNM1 | CYP19A1 3944/4885CES1 4840/4885ACHE 2669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.