Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.53 |
| ▸ | CTSL | P07711 | 18/20 | 0.53 |
| ▸ | CTSK | P43235 | 12/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688734 | 0.87 | CTSS (0.57) | CTSSCTSLCTSK | |
| SCHEMBL6688127 | 0.84 | CTSS (0.72) | CTSSCTSLCTSK | |
| SCHEMBL6687351 | 0.84 | CTSS (0.72) | CTSSCTSLCTSK | |
| SCHEMBL6694459 | 0.83 | CTSS (0.70) | CTSSCTSLCTSK | |
| SCHEMBL6697440 | 0.83 | CTSS (0.70) | CTSSCTSLCTSK | |
| SCHEMBL6690874 | 0.80 | TDP1 (0.47) | CTSSCTSLCTSKTDP1L3MBTL1 | |
| SCHEMBL6685718 | 0.78 | TDP1 (0.48) | CTSSCTSLCTSKTDP1L3MBTL1 | |
| SCHEMBL5843302 | 0.73 | CTSS (0.67) | CTSSCTSLCTSK | |
| SCHEMBL5843306 | 0.73 | CTSS (0.67) | CTSSCTSLCTSK | |
| SCHEMBL7471193 | 0.72 | CTSL (0.52) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |