SCHEMBL6690900

SCHEMBL6690900

CCCCOc1cccc2sc(SSc3nc4c(OCCCC)cccc4s3)nc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
MCHR1 Q99705 4/20 0.49
TDP1 Q9NUW8 3/20 0.47
KDM4E B2RXH2 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
MAPT P10636 2/20 0.47
PKM P14618 1/20 0.47
MAPK1 P28482 1/20 0.47
EPHX2 P34913 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
CYP3A4 P08684 1/20 0.40
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
DUSP3 P51452 1/20 0.40
FBP1 P09467 2/20 0.39
HPGD P15428 2/20 0.39
ADRA2A P08913 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6689028 0.93 ALDH1A1 (0.51) ALDH1A1MCHR1TDP1KDM4EMEN1
SCHEMBL6899949 0.91 ALDH1A1 (0.50) ALDH1A1MCHR1TDP1KDM4EMEN1
SCHEMBL6689165 0.87 ALDH1A1 (0.66) ALDH1A1TDP1KDM4EMEN1KMT2A
SCHEMBL6694180 0.85 KMT2A (0.45) ALDH1A1MCHR1TDP1KDM4EMEN1
SCHEMBL6697966 0.83 KMT2A (0.43) ALDH1A1MCHR1TDP1KDM4EMEN1
SCHEMBL6689421 0.82 ALDH1A1 (0.52) ALDH1A1MCHR1TDP1KDM4EMEN1
SCHEMBL6689479 0.79 ALDH1A1 (0.53) ALDH1A1MCHR1TDP1KDM4EMEN1
SCHEMBL6694941 0.79 ALDH1A1 (0.39) ALDH1A1MCHR1TDP1KDM4EMEN1
SCHEMBL6693695 0.79 ALDH1A1 (0.63) ALDH1A1TDP1KDM4EMEN1KMT2A
SCHEMBL6898848 0.78 ALDH1A1 (0.66) ALDH1A1TDP1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0869016-B1 Pneumatic radial tires BRIDGESTONE CORP (JP) 2004-03-03 EP disclosed
EP-0890605-B1 Pneumatic tire BRIDGESTONE CORP (JP) 2003-04-23 EP disclosed
EP-0854168-B1 Rubber composition BRIDGESTONE CORP (JP) 2003-04-02 EP disclosed
EP-1277795-A2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2003-01-22 EP disclosed
US-20020010283-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2002-01-24 US disclosed
US-6336486-B1 Pneumatic radical tire having cap base tread BRIDGESTONE CORPORATION (JP) 2002-01-08 US disclosed
US-6186204-B1 EXCELLENT STABILITY AND CONTROLLABILITY ON WET ROADS OR A COMBINATION OF STABILITY AND CONTROLLABILITY ON WET ROADS AND EXCELLENT COMFORT OF RIDE EVEN WHEN A VEHICLE IS VIBRATING THROUGHOUT THE LIFE OF THE PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2001-02-13 US disclosed
EP-0890605-A2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 1999-01-13 EP disclosed
EP-0869016-A2 Pneumatic radial tires Bridgestone Corporation (JP) 1998-10-07 EP disclosed
EP-0854168-A1 Rubber composition Bridgestone Corporation (JP) 1998-07-22 EP disclosed