Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933760 | 0.83 | CYP1A2 (0.57) | L3MBTL1KDM4EPTPN1PTPN11ALDH1A1 | |
| SCHEMBL2716691 | 0.78 | L3MBTL1 (0.70) | L3MBTL1KDM4EPTPN1PTPN11ALDH1A1 | |
| SCHEMBL9529688 | 0.78 | HPGD (0.70) | KDM4EALDH1A1GAAMAPTCYP1A2 | |
| SCHEMBL8782898 | 0.77 | L3MBTL1 (0.69) | L3MBTL1KDM4EPTPN1PTPN11ALDH1A1 | |
| SCHEMBL8322277 | 0.77 | L3MBTL1 (0.69) | L3MBTL1KDM4EPTPN1PTPN11ALDH1A1 | |
| SCHEMBL15456012 | 0.77 | L3MBTL1 (0.64) | L3MBTL1KDM4EPTPN1PTPN11ALDH1A1 | |
| SCHEMBL456924 | 0.77 | L3MBTL1 (0.69) | L3MBTL1KDM4EPTPN1PTPN11ALDH1A1 | |
| SCHEMBL4392892 | 0.77 | CYP2C19 (0.59) | ALDH1A1CYP1A2CYP3A4CYP2D6LMNA | |
| SCHEMBL28769847 | 0.76 | PTPN1 (0.53) | L3MBTL1KDM4EPTPN1PTPN11ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6298735 | 0.76 | L3MBTL1 (0.67) | L3MBTL1KDM4EPTPN1PTPN11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308297-C | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2007-04-04 | — | — | CN | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| CN-1360570-A | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2002-07-24 | — | — | CN | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |