SCHEMBL6691222

SCHEMBL6691222

CC(=O)NCOc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 10/20 0.68
MTNR1B P49286 10/20 0.68
L3MBTL1 Q9Y468 1/20 0.66
ALOX15 P16050 2/20 0.50
POLB P06746 1/20 0.49
PKM P14618 1/20 0.49
RECQL P46063 1/20 0.49
USP2 O75604 1/20 0.49
TSHR P16473 1/20 0.49
MAPK1 P28482 1/20 0.49
HSD17B10 Q99714 1/20 0.49
HPGD P15428 2/20 0.47
RAB9A P51151 2/20 0.47
KMT2A Q03164 1/20 0.47
NPC1 O15118 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anisole SCHEMBL28832564 0.93 MTNR1A (0.60) MTNR1AMTNR1BL3MBTL1RECQLTSHR
SCHEMBL9795692 0.86 MTNR1A (0.61) MTNR1AMTNR1BL3MBTL1
SCHEMBL1701975 0.83 ALOX15 (0.54) MTNR1AMTNR1BL3MBTL1ALOX15PKM
SCHEMBL9487171 0.83 MTNR1A (0.53) MTNR1AMTNR1BL3MBTL1ALOX15POLB
SCHEMBL1027989 0.82 MTNR1A (0.51) MTNR1AMTNR1BL3MBTL1ALOX15POLB
SCHEMBL885015 0.81 MTNR1A (1.00) MTNR1AMTNR1BL3MBTL1ALOX15POLB
SCHEMBL11697243 0.80 ALDH1A1 (0.49) MTNR1AMTNR1BL3MBTL1ALOX15POLB
SCHEMBL11408464 0.80 ALOX15 (0.50) MTNR1AMTNR1BL3MBTL1ALOX15PKM
SCHEMBL11410282 0.80 PARP10 (0.50) MTNR1AMTNR1BL3MBTL1ALOX15PKM
SCHEMBL3225336 0.78 NPC1 (0.69) POLBRECQLHPGDRAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0263951-B1 Disazo compounds and compositions containing them BASF LACKE & FARBEN (DE) 1994-06-15 EP claimed
CN-113773223-B Method for purifying 2-amino-4-acetamino anisole by precipitation method 山东理工大学 2023-08-01 CN disclosed
CN-112778308-A Fused tricyclic derivatives as FGFR4 inhibitors 齐鲁制药有限公司 2021-05-11 CN disclosed
EP-0950669-B1 Method of catalytic crosslinking of polymers and two-pack composition used therein ROHM & HAAS (US) 2004-09-08 EP disclosed
US-6306991-B1 TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS ROHM AND HAAS COMPANY 2001-10-23 US disclosed
US-6149977-A CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. ROHM AND HAAS COMPANY (US) 2000-11-21 US disclosed
WO-2000051969-A1 OXYALKYLENE-SUBSTITUTED m-AMIDOANILINE INTERMEDIATE MILLIKEN & CO. (US) 2000-09-08 WO disclosed
US-6069276-A Oxyalkylene-substituted m-amidoaniline intermediate MILLIKEN & COMPANY (US) 2000-05-30 US disclosed
EP-0950669-A2 Method of catalytic crosslinking of polymers and two-pack composition used therein ROHM AND HAAS COMPANY (US) 1999-10-20 EP disclosed
US-5637591-A TREATMENT OF GINGIVITIS FUJI IMMUNOPHARMACEUTICALS CORP. (US) 1997-06-10 US disclosed
EP-0212303-A2 Process for the preparation of aromatic dialkyl amines HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-04 EP disclosed
EP-0023557-A1 Process for the preparation of substituted nitroaryl compounds CIBA-GEIGY AG (CH) 1981-02-11 EP disclosed