Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848979 | 0.83 | KDM4E (0.51) | ALDH1A1LMNAKDM4EPOLBPLA2G4B | |
| SCHEMBL28429277 | 0.83 | L3MBTL1 (0.69) | ALDH1A1LMNAKDM4EPLA2G4BPPARD | |
| SCHEMBL11685327 | 0.82 | LTB4R (0.43) | ALDH1A1LMNAKDM4EPOLBPLA2G4B | |
| SCHEMBL6691222 | 0.80 | MTNR1A (0.68) | POLBUSP2ALOX15TSHRMAPK1 | |
| SCHEMBL11687328 | 0.78 | KDM4E (0.45) | ALDH1A1LMNAKDM4EPOLBPLA2G4B | |
| SCHEMBL11686360 | 0.78 | LTB4R (0.43) | ALDH1A1LMNAKDM4EPOLBPLA2G4B | |
| SCHEMBL11698241 | 0.78 | KMT2A (0.49) | ALDH1A1LMNAKDM4EPOLBPPARD | |
| SCHEMBL11209134 | 0.77 | CA2 (0.52) | LMNAKDM4EPOLBPLA2G4BPPARD | |
| SCHEMBL5210398 | 0.77 | KMT2A (0.67) | ALDH1A1LMNAPOLBTSHRHSD17B10 | |
| SCHEMBL503308 | 0.77 | PLA2G4B (0.58) | ALDH1A1POLBPLA2G4BMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4005088-A | Process for the chemical separation of racemic modifications of α-aminocarboxylic acid derivatives, and cinchonidine salt intermediates | ANDENO B.V. (NL) | 1977-01-25 | — | — | US | disclosed |