SCHEMBL6691641

SCHEMBL6691641

O=C(CF)Nc1ccc(C(=O)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MITF O75030 1/20 0.55
CA12 O43570 2/20 0.54
CA2 P00918 2/20 0.54
CA9 Q16790 2/20 0.54
ALDH1A1 P00352 3/20 0.52
CYP1A2 P05177 1/20 0.51
CYP2C9 P11712 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CA1 P00915 1/20 0.50
POLB P06746 1/20 0.49
GAA P10253 1/20 0.49
FFAR1 O14842 1/20 0.49
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
HSD17B10 Q99714 1/20 0.48
STAT3 P40763 1/20 0.48
EPHX2 P34913 2/20 0.47
HPGD P15428 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28010779 0.85 POLB (0.57) MITFCA12CA2CA9ALDH1A1
SCHEMBL2843886 0.82 CA12 (0.56) MITFCA12CA2CA9ALDH1A1
SCHEMBL9912437 0.82 CA12 (0.56) MITFCA12CA2CA9ALDH1A1
SCHEMBL2781923 0.81 EPHX2 (0.61) ALDH1A1MEN1KMT2AGAATP53
SCHEMBL216113 0.80 CA12 (0.54) MITFCA12CA2CA9ALDH1A1
SCHEMBL2940113 0.80 ALDH1A1 (0.65) MITFCA12CA2CA9ALDH1A1
SCHEMBL1663647 0.80 CA2 (0.58) MITFCA12CA2CA9ALDH1A1
SCHEMBL1395934 0.80 ALDH1A1 (0.71) CA12CA2CA9ALDH1A1CYP1A2
SCHEMBL2344100 0.80 CA12 (0.54) MITFCA12CA2CA9ALDH1A1
SCHEMBL3911049 0.80 CA12 (0.54) MITFCA12CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4569330-A1 NOVEL PORE MONOMERS AND PORES Oxford Nanopore Technologies PLC (GB) 2025-06-18 EP disclosed
CN-119630970-A Novel Kong Shanti and holes 牛津纳米孔科技公开有限公司 2025-03-14 CN disclosed
WO-2024033443-A1 NOVEL PORE MONOMERS AND PORES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-02-15 WO disclosed
EP-0950669-B1 Method of catalytic crosslinking of polymers and two-pack composition used therein ROHM & HAAS (US) 2004-09-08 EP disclosed
US-6306991-B1 TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS ROHM AND HAAS COMPANY 2001-10-23 US disclosed
US-6149977-A CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. ROHM AND HAAS COMPANY (US) 2000-11-21 US disclosed
EP-0950669-A2 Method of catalytic crosslinking of polymers and two-pack composition used therein ROHM AND HAAS COMPANY (US) 1999-10-20 EP disclosed