Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15267699 | 0.87 | KMT2A (0.60) | ALDH1A1MEN1KMT2AMITFPOLB | |
| SCHEMBL28010779 | 0.85 | POLB (0.57) | CA12CA2CA9ALDH1A1CYP1A2 | |
| SCHEMBL6932060 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APOLBTP53 | |
| SCHEMBL7687241 | 0.82 | MAPT (0.62) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL2843886 | 0.82 | CA12 (0.56) | CA12CA2CA9ALDH1A1CYP1A2 | |
| SCHEMBL9912437 | 0.82 | CA12 (0.56) | CA12CA2CA9ALDH1A1CYP1A2 | |
| SCHEMBL230627 | 0.81 | HDAC4 (0.62) | MEN1KMT2AGAATP53TSHR | |
| SCHEMBL1561735 | 0.80 | CYP1A2 (0.60) | CYP1A2CYP2C9 | |
| SCHEMBL1663647 | 0.80 | CA2 (0.58) | CA12CA2CA9ALDH1A1CYP1A2 | |
| SCHEMBL2940113 | 0.80 | ALDH1A1 (0.65) | CA12CA2CA9ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353152-B2 | Induction of the mitochondrial permeability transition | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2016-05-31 | — | — | US | disclosed |
| US-8921515-B2 | Methods and compositions of preparation for proteome analysis | CASE WESTERN RESERVE UNIVERSITY (US) | 2014-12-30 | — | — | US | disclosed |
| US-20140121165-A1 | Induction of the Mitochondrial Permeability Transition | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2014-05-01 | — | — | US | disclosed |
| US-20130172539-A1 | METHODS AND COMPOSITIONS OF PREPARATION FOR PROTEOME ANALYSIS | CASE WESTERN RESERVE UNIVERSITY (US) | 2013-07-04 | — | — | US | disclosed |
| EP-2088206-B1 | Induction of the mitochondrial permeability transition | NEWSOUTH INNOVATIONS PTY LTD (AU) | 2013-07-03 | — | — | EP | disclosed |
| EP-2088206-A2 | Induction of the mitochondrial permeability transition | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2009-08-12 | — | — | EP | disclosed |
| EP-1563099-B1 | INDUCTION OF THE MITOCHONDRIAL PERMEABILITY TRANSITION | NEWSOUTH INNOVATIONS PTY LTD (AU) | 2009-07-22 | — | — | EP | disclosed |
| EP-1686188-B1 | Thin membrane for measuring protease activity | FUJIFILM CORP (JP) | 2009-03-18 | — | — | EP | disclosed |
| EP-1270736-B1 | FILMS FOR ASSAYING PROTEASE ACTIVITY | FUJIFILM CORP (JP) | 2009-03-11 | — | — | EP | disclosed |
| EP-1686188-A1 | Thin membrane for measuring protease activity | Fuji Photo Film Co. Ltd. (JP) | 2006-08-02 | — | — | EP | disclosed |
| WO-2003003011-A1 | MODIFICATION OF ANGIOGENESIS BY TARGETING PROTEIN TYROSINE PHOSPHATASES | UNISEARCH LIMITED (AU) | 2003-01-09 | — | — | WO | disclosed |
| EP-1270736-A1 | FILMS FOR ASSAYING PROTEASE ACTIVITY | FUJI PHOTO FILM CO., LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6306991-B1 | TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS | ROHM AND HAAS COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6149977-A | CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. | ROHM AND HAAS COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0950669-A2 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM AND HAAS COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |
| US-5741926-A | ANTIDIABETIC AGENT | SHAMAN PHARMACEUTICALS, INC. (US) | 1998-04-21 | — | — | US | disclosed |
| WO-1997030019-A1 | ANILINE DERIVATIVES HAVING ANTIHYPERGLYCEMIC ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1997-08-21 | — | — | WO | disclosed |
| US-4536346-A | TREATMENT OF ATHEROSCLEROSIS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | disclosed |
| EP-0124791-A1 | Aralkanamidophenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1984-11-14 | — | — | EP | disclosed |
| US-4102924-A | REACTING ACYLAMINO-ARYLS WITH HALO-ARYLS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140121165-A1 | Induction of the Mitochondrial Permeability Transition | TFAM, NME4, TIMM50 | CA12 3865/4885CA2 2015/4885CA9 3293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.