Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.62 |
| ▸ | PPARG | P37231 | 4/20 | 0.61 |
| ▸ | PPARA | Q07869 | 4/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.58 |
| ▸ | LTA4H | P09960 | 2/20 | 0.58 |
| ▸ | PPARD | Q03181 | 1/20 | 0.58 |
| ▸ | LAP3 | P28838 | 1/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6312211 | 0.90 | LTA4H (0.65) | MAOBPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL4855268 | 0.89 | LMNA (0.62) | MAOBPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL7801265 | 0.89 | PPARA (0.70) | MAOBPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL2603686 | 0.86 | LTA4H (0.64) | MAOBPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL14501342 | 0.86 | MAOB (0.61) | MAOBPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL14559932 | 0.86 | LTA4H (0.64) | MAOBPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL14501338 | 0.86 | MAOB (0.61) | MAOBPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL14501335 | 0.86 | MAOB (0.60) | MAOBPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL17484675 | 0.86 | LTA4H (0.64) | MAOBPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL16743935 | 0.85 | MAOB (0.61) | MAOBPPARGPPARAFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |
| US-5453514-A | Diabetes | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-09-26 | — | — | US | disclosed |