Benzidine

Benzidine

SCHEMBL6692243

Nc1ccc(-c2ccc(N)cc2)cc1.O=Cc1ccc(F)c(F)c1.O=Cc1ccc(F)c(F)c1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.45
ALDH1A1 P00352 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP3A4 P08684 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
TP53 P04637 1/20 0.41
TAAR1 Q96RJ0 2/20 0.40
NFE2L2 Q16236 2/20 0.39
DRD1 P21728 2/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
ERN1 O75460 1/20 0.36
KDM4E B2RXH2 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.35
CYP19A1 P11511 1/20 0.35
PTGS2 P35354 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL27687525 0.84 ALDH1A1 (0.48) KIF11ALDH1A1SMN1; SMN2TDP1NFE2L2
SCHEMBL48607 0.84 ALDH1A1 (0.52) KIF11ALDH1A1SMN1; SMN2TDP1NFE2L2
SCHEMBL29389102 0.84 ALDH1A1 (0.52) KIF11ALDH1A1SMN1; SMN2TDP1NFE2L2
SCHEMBL4808094 0.82 ALDH1A1 (0.50) KIF11ALDH1A1SMN1; SMN2TDP1NFE2L2
SCHEMBL3457040 0.80 KIF11 (0.65) KIF11ALDH1A1SMN1; SMN2NFE2L2DRD1
SCHEMBL21908192 0.80 ALDH1A1 (0.58) KIF11ALDH1A1CYP3A4TDP1TP53
SCHEMBL13659420 0.80 ALDH1A1 (0.58) KIF11ALDH1A1CYP3A4TDP1TP53
Hydrochloric Acid SCHEMBL11478183 0.78 ALDH1A1 (0.55) KIF11ALDH1A1CYP3A4TDP1TP53
SCHEMBL14054493 0.78 KIF11 (0.61) KIF11ALDH1A1SMN1; SMN2CYP3A4TDP1
SCHEMBL31388656 0.78 KIF11 (0.61) KIF11ALDH1A1SMN1; SMN2CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472319-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2004-11-03 EP disclosed
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed