Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692490 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10HCAR2KEAP1 | |
| SCHEMBL11959876 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10HCAR2KEAP1 | |
| SCHEMBL8923357 | 0.77 | HCAR2 (0.40) | TSHRHCAR2KEAP1NFE2L2 | |
| SCHEMBL8752313 | 0.77 | HCAR2 (0.40) | TSHRHCAR2KEAP1NFE2L2 | |
| SCHEMBL713656 | 0.77 | NPSR1 (0.48) | ALDH1A1TSHRHSD17B10HCAR2CYP1A2 | |
| SCHEMBL21673002 | 0.77 | NPSR1 (0.48) | ALDH1A1TSHRHSD17B10HCAR2CYP1A2 | |
| SCHEMBL713655 | 0.77 | NPSR1 (0.48) | ALDH1A1TSHRHSD17B10HCAR2CYP1A2 | |
| SCHEMBL18681846 | 0.76 | HCAR2 (0.43) | ALDH1A1HCAR2KEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL15482813 | 0.74 | HCAR2 (0.42) | ALDH1A1TSHRHSD17B10HCAR2KEAP1 | |
| SCHEMBL15482751 | 0.74 | HCAR2 (0.42) | ALDH1A1TSHRHSD17B10HCAR2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040254206-A1 | Substituted phenyluracils | ANDREE ROLAND (DE) | 2004-12-16 | — | — | US | disclosed |
| US-6815398-B1 | PRE- AND POSTEMERGENCE HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-09 | — | — | US | disclosed |
| US-6780821-B1 | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-24 | — | — | US | disclosed |
| US-20040029735-A1 | Substituted herbicidal phenyluracils | ANDREE ROLAND (DE) | 2004-02-12 | — | — | US | disclosed |
| US-20040023805-A1 | Substituted phenyluracils | ANDREE ROLAND (DE) | 2004-02-05 | — | — | US | disclosed |
| US-6649760-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-18 | — | — | US | disclosed |
| US-6624120-B1 | Such as 1-(4-cyano-2-fluoro-5-(6-methoxy-naphthalen-2-yl-oxy)-phenyl)-2,6-dioxo -1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-23 | — | — | US | disclosed |
| CN-1420873-A | Substituted phenyluracils | BAYER AG (DE) | 2003-05-28 | — | — | CN | disclosed |
| US-6528455-B1 | Post or preemergence herbicides such as 3-(4-chloro-2-fluoro -5-(1-methoxycarbonyl-1-vinyloxy)phenyl)-1-methyl-6-trifluoro methyl-2,4-pyrimidinedione | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-04 | — | — | US | disclosed |
| US-20020173425-A1 | Substituted phenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-21 | — | — | US | disclosed |
| US-6423866-B1 | THERMOLYSIS OF AMMONIUM SALT OF HALOGENATED LOWER ALKYL ACETOACETATE USING MELT | SOLVAYTFLOUR UND DERIVATE GMBH (DE) | 2002-07-23 | — | — | US | disclosed |
| US-5888940-A | DESICCATING PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-30 | — | — | US | disclosed |
| EP-0862569-A1 | SUBSTITUTED BENZOTHIAZOLS WITH HERBICIDAL ACTION | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997008171-A1 | SUBSTITUTED BENZOTHIAZOLS WITH HERBICIDAL ACTION | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-06 | — | — | WO | disclosed |
| US-4964895-A | Substituted 4-(4-nitrophenoxy) pyrazoles and their use as herbicides | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4948902-A | Process for making substituted pyrazoles | MONSANTO COMPANY (US) | 1990-08-14 | — | — | US | disclosed |
| EP-0295233-A2 | Substituted 3-(4-nitrophenoxy)pyrazoles and their use as herbicides | Monsanto Company (US) | 1988-12-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173425-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | ALDH1A1 44/4885TSHR 920/4885HSD17B10 2520/4885 |
| US-20040029735-A1 | Substituted herbicidal phenyluracils | DDT, MTX1, MTX2 | ALDH1A1 124/4885TSHR 1425/4885HSD17B10 1441/4885 |
| US-20040023805-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | ALDH1A1 44/4885TSHR 920/4885HSD17B10 2520/4885 |
| US-20040254206-A1 | Substituted phenyluracils | DPYD, NDUFS5, POP1 | ALDH1A1 96/4885TSHR 1705/4885HSD17B10 2460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.