Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096248 | 0.80 | LMNA (0.61) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL1747928 | 0.79 | LMNA (0.66) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL2433144 | 0.78 | LMNA (0.63) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL30189774 | 0.76 | LMNA (0.61) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL21395484 | 0.76 | LMNA (0.61) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL103727 | 0.76 | LMNA (1.00) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL2615997 | 0.76 | LMNA (0.61) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL3424292 | 0.76 | LMNA (0.61) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL5339377 | 0.76 | ALDH1A1 (0.61) | LMNAALDH1A1MAPTHPGDGAA | |
| SCHEMBL5820155 | 0.76 | PDPK1 (0.61) | LMNAPDE10AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078115-A2 | BENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF ROTAVIRUS INFECTIONS AND ASSOCIATED DISEASES | VIROPHARMA, INCORPORATED (US) | 2004-09-16 | — | — | WO | disclosed |