Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679660 | 0.95 | CTSD (0.40) | CTSDADRB3ADRB2ADRB1ABCC9 | |
| SCHEMBL6678492 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MAPTADRB3ADRB2ADRB1 | |
| SCHEMBL6676613 | 0.86 | SIGMAR1 (0.39) | ALDH1A1ADRB3ADRB2ADRB1SLC2A1 | |
| SCHEMBL6682215 | 0.85 | ADRB3 (0.42) | ADRB3ADRB1 | |
| SCHEMBL6678008 | 0.84 | ADRB3 (0.41) | CTSDADRB3ADRB2ADRB1SLC2A1 | |
| SCHEMBL6681933 | 0.82 | ADRB3 (0.42) | ALDH1A1MAPTADRB3ADRB2ADRB1 | |
| SCHEMBL6677081 | 0.81 | CYP4F2 (0.42) | ALDH1A1MAPTADRB3ADRB2ADRB1 | |
| SCHEMBL6676287 | 0.81 | ADRB3 (0.55) | ADRB3ADRB1 | |
| SCHEMBL6679483 | 0.81 | SLC2A1 (0.39) | ADRB3ADRB2ADRB1SLC2A1 | |
| SCHEMBL6679282 | 0.81 | SLC2A1 (0.39) | ADRB3ADRB2ADRB1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |