Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694938 | 0.81 | OPRM1 (0.42) | KMT2AMEN1ALDH1A1GLATSHR | |
| SCHEMBL28665242 | 0.79 | KMT2A (0.47) | KMT2AMEN1ALDH1A1GLATSHR | |
| SCHEMBL11238745 | 0.79 | LMNA (0.38) | KMT2AMEN1ALDH1A1GLATSHR | |
| Hydrochloric Acid SCHEMBL11074227 | 0.78 | ALDH1A1 (0.36) | KMT2AALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL11211446 | 0.78 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1GLATSHR | |
| SCHEMBL23116471 | 0.76 | TP53 (0.56) | KMT2AMEN1ALDH1A1GLATSHR | |
| SCHEMBL6699646 | 0.76 | NPSR1 (0.36) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6691763 | 0.76 | NPSR1 (0.36) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6695686 | 0.76 | NPSR1 (0.36) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL28515349 | 0.76 | NPSR1 (0.36) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3553083-B2 | — | — | 2004-08-11 | — | — | JP | claimed |
| EP-0852494-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-07-15 | — | — | EP | claimed |
| WO-1997009973-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-03-20 | — | — | WO | claimed |