Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12443096 | 0.85 | L3MBTL1 (0.40) | LMNAL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10890513 | 0.85 | LMNA (0.45) | LMNAL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10857210 | 0.83 | CA1 (0.37) | PLAUKMT2AALDH1A1TSHR | |
| SCHEMBL6695686 | 0.82 | NPSR1 (0.36) | L3MBTL1PLAUMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28515349 | 0.82 | NPSR1 (0.36) | L3MBTL1PLAUMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10729162 | 0.82 | NPSR1 (0.36) | L3MBTL1PLAUMEN1KMT2ANPSR1 | |
| SCHEMBL6699646 | 0.82 | NPSR1 (0.36) | L3MBTL1PLAUMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6691763 | 0.82 | NPSR1 (0.36) | L3MBTL1PLAUMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6694938 | 0.81 | OPRM1 (0.42) | L3MBTL1PLAUMEN1KMT2AALDH1A1 | |
| SCHEMBL10857082 | 0.81 | ALDH1A1 (0.41) | LMNAL3MBTL1SIRT2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338441-A | CYCLIZATION OF AMIDINOUREA OR AMIDINOTHIOUREA WITH ACTIVE METHYLIDENE COMPOUND | WILLIAM H. RORER, INC. (US) | 1982-07-06 | — | — | US | claimed |